Lyprinol: A Timeline - Over 27 years of experience and research.

The Australian MacLab group acquire an interest in some mussel farming operations. They set out to develop Green Lipped Mussel extract. Could use this link to discuss potency and the difference between competitors

The MacLab Group discovers and patents a process to stabilise the non-polar lipid activity in the mussel. The meat can now be safely freeze-dried and powdered; the essential non-polar lipids extracted. The new product is marketed as Seatone in Australia and New Zealand. The UK market opens shortly after.

Dr. Sheila Gibson and Dr. Robert Gibson produce research in Glasgow indicating the mussel extract has certain anti-inflammatory properties.

The results are published in The Practitioner. Questions arise from the medical community when other researchers cannot repeat the results.

The MacLab Group, with some UK partners, purchase a mussel powder factory in New Zealand. They establish a research project at the Natural Products Chemistry Division of the Royal Melbourne Institute of Technology (RMIT) in Australia.

Jim Broadbent from the MacLab Group meets Professor Takuo Kosuge from the Shizuoka University in Japan. As a leading authority on natural products chemistry, Prof. Kosuge offers the help of his group to RMIT. He concludes that powder from the Green Lipped Mussel is very unstable, meaning it oxidises rapidly.

Professor Kosuge tries all recognised antioxidants, without success. Finally, he turns to an ancient Japanese technique used by Japanese fisherman to store fish in a special solution. The results are spectacular: oxidisation is halted.

Despite the success, disagreement with their partners force the MacLab Group to sell the Seatone trademark for most countries to their UK partners.

Dr Henry Betts, Principal Scientist at the Rheumatology Research Laboratory at the Queen Elizabeth Hospital, Adelaide, tests fractions extracted from the Green Lipped Mussel. He claims that two of these are the most active compounds he's ever tested.

Dr. Michael Whitehouse begins in vivo animal tests to identify the areas of activity of the Green Lipped Mussel's active components.

Methods of super critical fluid extraction (SFE) are developed to commercially extract the active components from the Green Lipped Mussel. The process uses liquefied carbon dioxide and no chemical solvents. As a result, the MacLab group applies for 4 international patents:

1. Stabilisation Patent - for the process of stabilising the active lipids in the mussel before they oxidise
2. Patent of Active Fractions - for the isolation of the active fractions within the mussel.
3. Extraction Process Patent - for the process of lipid extraction without chemical residues
4. Usage Patents - for Lyprinol to be used as an anti-inflammatory